NovoMCP

Tracking since May 12, 2026.

Changelog

• Jun 6, 2026
  description

  Hover any molecule on PubChem, ChEMBL, bioRxiv, medRxiv, or arXiv and see what matters before you click away.
  
  NovoMCP adds a molecular intelligence layer to the scientific pages you already read. When you encounter a SMILES string, the extension surfaces a profile card with physicochemical properties, drug-likeness scores, and structural alerts. Click through to the side panel for the full picture: ADMET predictions, regulatory compliance screening, and structurally similar compounds across 100M+ indexed molecules.
  
  Every lookup is tied to a session you can pick up later in Claude, ChatGPT, Gemini, NovoWorkbench, or any other AI assistant connected to NovoMCP. Copy the "Continue in AI" prompt and your full context carries over: compounds, predictions, compliance flags, everything. Your audit trail is preserved and viewable at app.novomcp.com.
  
  PROFILE TAB
  Molecular weight, logP, TPSA, hydrogen bond donors/acceptors, rotatable bonds, aromatic rings
  Lipinski, Veber, Ghose, Egan, and Muegge drug-likeness rule checks
  QED drug-likeness score
  Structural alerts (PAINS, Brenk, unwanted substructures)
  
  ADMET TAB
  ML model predictions covering absorption, distribution, metabolism, excretion, and toxicity
  Radar chart visualization for quick assessment
  Severity-coded cards for each endpoint
  
  COMPLIANCE TAB
  FAVES regulatory screening across 8 jurisdictions
  Controlled substance flags
  Context-aware assessment when connected to NovoMCP
  
  SIMILAR TAB
  Search for structurally similar compounds across 100M+ indexed molecules
  Adjustable similarity threshold (0.3 to 0.7)
  Results with similarity scores and key property comparisons
  
  ADVANCED TAB (Novo Compute subscription)
  pKa predictions with site-by-site ionization interpretation
  Aqueous solubility (logS) with category labels
  Bond dissociation energies for metabolic soft-spot detection
  HOMO/LUMO/gap frontier orbital calculations for materials and pharmacophore work
  
  SUPPORTED SITES
  PubChem (pubchem.ncbi.nlm.nih.gov)
  ChEMBL (ebi.ac.uk/chembl)
  bioRxiv (biorxiv.org)
  medRxiv (medrxiv.org)
  arXiv (arxiv.org)
  
  GETTING STARTED
  1. Install the extension
  2. Click the NovoMCP icon and follow the popup to connect your API key
  3. Browse any supported site, then hover a SMILES string to see the profile card
  4. Click "Open side panel" for the full breakdown
  
  The 7-day free trial includes 750 credits. Each profile lookup costs 1 credit; similarity searches cost 5 credits; Advanced compute calls vary by tool. Research groups and academic labs can apply for the research preview tier at novomcp.com/apply for an expanded credit envelope.
  
  PRIVACY
  SMILES strings you hover or click are sent to NovoMCP servers along with the originating domain (domain only, no URL path, query string, or page content is transmitted). Your API key is stored locally in chrome.storage.local, sandboxed to this extension. No browsing history is collected. No PII beyond your account email. No cross-site tracking. Full privacy policy at novomcp.com/privacy.
  
  NovoMCP: computational infrastructure for drug discovery and materials science.

  Hover any molecule on PubChem, ChEMBL, bioRxiv, medRxiv, or arXiv and see what matters before you click away.
  
  NovoMCP brings the computational chemistry engine into the scientific pages you already read. When you encounter a SMILES string, the extension surfaces a profile card with physicochemical properties, drug-likeness scores, and structural alerts. Click through to the side panel for the full picture: ADMET predictions, regulatory compliance screening, and structurally similar compounds across 100M+ indexed molecules.
  
  Every lookup is tied to a session you can pick up later in Claude, ChatGPT, Gemini, NovoWorkbench, or any other AI assistant connected to NovoMCP. Copy the "Continue in AI" prompt and your full context carries over: compounds, predictions, compliance flags, everything. Your audit trail is preserved and viewable at app.novomcp.com.
  
  PROFILE TAB
  Molecular weight, logP, TPSA, hydrogen bond donors/acceptors, rotatable bonds, aromatic rings
  Lipinski, Veber, Ghose, Egan, and Muegge drug-likeness rule checks
  QED drug-likeness score
  Structural alerts (PAINS, Brenk, unwanted substructures)
  
  ADMET TAB
  NovoExpert ADMET predictions across absorption, distribution, metabolism, excretion, and toxicity
  Radar chart visualization for quick assessment
  Severity-coded cards for each endpoint
  
  COMPLIANCE TAB
  FAVES V4 regulatory screening across 8 jurisdictions
  Controlled substance flags
  Context-aware assessment when connected to NovoMCP
  
  SIMILAR TAB
  Search for structurally similar compounds across 100M+ indexed molecules
  Adjustable similarity threshold (0.3 to 0.7)
  Results with similarity scores and key property comparisons
  
  ADVANCED TAB (Novo Compute subscription)
  pKa predictions with site-by-site ionization interpretation
  Aqueous solubility (logS) with category labels
  Bond dissociation energies for metabolic soft-spot detection
  HOMO/LUMO/gap frontier orbital calculations for materials and pharmacophore work
  
  SUPPORTED SITES
  PubChem (pubchem.ncbi.nlm.nih.gov)
  ChEMBL (ebi.ac.uk/chembl)
  bioRxiv (biorxiv.org)
  medRxiv (medrxiv.org)
  arXiv (arxiv.org)
  
  GETTING STARTED: 
  Install the extension
  Click the NovoMCP icon and follow the popup to connect your API key
  Browse any supported site, then hover a SMILES string to see the profile card
  Click "Open side panel" for the full breakdown
  
  The 7-day free trial includes 750 credits. Each profile lookup costs 1 credit; similarity searches cost 5 credits; Advanced compute calls vary by tool. Research groups and academic labs can apply for the research preview tier at novomcp.com/apply for an expanded credit envelope.
  
  PRIVACY
  SMILES strings you hover or click are sent to NovoMCP servers along with the originating domain (domain only, no URL path, query string, or page content is transmitted). Your API key is stored locally in chrome.storage.local, sandboxed to this extension. No browsing history is collected. No PII beyond your account email. No cross-site tracking. Full privacy policy at novomcp.com/privacy.
  
  NovoMCP: the computational chemistry engine for drug discovery and materials science.

Permissions & access

Permissions

storageactiveTabsidePanel

Host access

https://api.novomcp.com/*, https://novomcp.com/*, https://app.novomcp.com/*, https://ai.novomcp.com/*, https://compute.novomcp.com/*, https://pubchem.ncbi.nlm.nih.gov/*, https://www.ebi.ac.uk/chembl/*, https://www.biorxiv.org/*, https://www.medrxiv.org/*, https://arxiv.org/*

Screenshots